Download

Download Full Text (155.0 MB)

Description

The first Louisiana Tumor Registry (LTR) monograph provided background data on the Louisiana population, mortality rates for the state as well as incidence rates for the New Orleans metropolitan area compared to those of the United States. The second monograph focused on the magnitude of the cancer problem in Louisiana and the cancer mortality profile of our state as compared to other states. The third monograph described the new additions to the incidence oriented registry, provided data on time trends of cancer incidence in greater New Orleans, comparisons with SEER registries and age-specific incidence rates . The present (fourth) monograph provides mortality rates for the four regions of the state: Acadiana, Baton Rouge and Florida parishes, Northern Louisiana and Greater New Orleans, as well as comparable data for the state as a whole and for the United States . The time trends of each region are provided for four sex-race groups. Age-specific mortality rates for the state are presented and compared with those of the United States. In addition, abstracts of final reports of research grants funded by the Louisiana Cancer and Lung Trust Fund Board in 1985 are included. The four monographs, therefore, provide abundant data on cancer frequency in the state which hopefully will be utilized by the scientific and lay communities to better understand our cancer problem and develop strategies to deal with it. The cover of this monograph illustrates the marked decreases in Hodgkin's disease mortality observed in all regions of the state. Since the incidence of this neoplastic disease has not decreased (Monograph III), these decreases in mortality most probably indicate advances in therapy, which should bring some optimism to our community and reassure our medical care personnel that their actions are having a positive impact on the health of our population . Geographic analysis reveals excesses in mortality Greater New Orleans for cancers of the oral cavity and pharynx, colon, rectum, and bladder as well as kidney cancer in males only. Acadiana shows excesses for cancer of the stomach, pancreas, esophagus (males only), larynx (blacks only) and kidney (females only). Baton Rouge shows excess malignant melanoma rates. Cancer of the cervix is excessive in North Louisiana. Rectal cancer mortality is also decreasing in all race-sex groups which agrees with the incidence trends in males but contrasts with incidence trends in females (Monograph III). Cancer of the stomach and cancer of the cervix show marked decreases in mortality rates over time in blacks. Such trends are not clear in whites, perhaps because marked reductions in the rates for these cancers in whites took place years ago. Respiratory cancer rates continue to increase in blacks while trends are decreasing for laryngeal cancer in whites and apparently leveling-off for lung cancer in white males. These trends may reflect changes in the smoking habits of the race-sex groups being considered. The figures also show an increase in kidney cancer in black females in all regions. Liver cancer is decreasing in whites but increasing in blacks and shifting its apparent cluster from Acadiana to the greater New Orleans area. The structures of the age-specific curves reveal some interesting patterns. Cancers of the oral cavity and pharynx, esophagus and larynx exhibit 2-slope or dome shaped curves, which suggest either a non-homogenous delivery of carcinogens over time or an increase in incidence in younger cohorts by the introduction of a new carcinogen or an increase in the dose of an old one. Pre-menopausal peaks in both incidence and mortality from cervical cancer have been found in Louisiana data for both races in both time periods. Other atypical mortality curves which need further research are those of cancers of the ovary, bladder, kidney and multiple myeloma.

Publication Date

1-1-1987

Publisher

Louisiana Tumor Registry

Comments

The Louisiana Tumor Registry can be reached at LTR-info@lsuhsc.edu

Cancer in Louisiana: Volume 4

Share

COinS