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This fifth volume of "Cancer In Louisiana" Is the first to focus exclusively on childhood cancer. In view of the relatively small population at risk, ten years of data from the Louisiana Tumor Registry have been analyzed, from 1974 through 1983. Cancer Incidence reports are available for this period only from the Greater New Orleans area, comprising the parishes of Jefferson, Orleans, and St. Bernard. (Mortality figures, however, are available for the entire state.) Comparison Is made with the Incidence rates for the SEER program from 1974 through 1983, as derived from the SEER user tape (1) and the SEER population tape (2). The first four volumes of "Cancer In Louisiana" dealt primarily with adult cancers, of which the overwhelming majority are carcinomas (epithelial tumors). For adult tumors, therefore, It was appropriate to use a classlflcatlon system based primarily on anatomical site. In children, however, carcinomas are exceedingly rare. Most pediatric tumors are sarcomas, lymphomas, leukemias, or primitive embryonal cell lines which are not necessarily limited to a specific part of the body. Therefore, it is more appropriate to classify pediatric tumors according to histology rather than anatomic site. The classification scheme used In this volume Is adapted from the "Manchester" classification as reported In the literature (3) and adopted by the International Agency for Research on Cancer (4). In this classlflcatlon scheme, most pediatric tumor types fall into one of ten major groups. An eleventh group Is reserved for the occasional carcinomas, and all other tumors fall Into the twelfth category. For each of the ten maJor pediatric cancer groups, Incidence rates per million child-years-at-risk have been calculated. Most of the ten major groups can be subdivided Into several distinct histologlc subtypes. For each subtype, the numbers of cases have been tabulated by age, sex, and race, but Incidence rates have not been calculated because of the smal I numbers of cases. Charts and graphs have been prepared to compare cancer Incidence rates for each tumor type between males and females, between blacks and whites, between New Orleans children and children In the SEER program, and between the various hlstologlc subtypes. The reader Is cautioned to observe the +/- one standard error which Is Included In the table of rates. 95% confidence Intervals (+/- two standard errors) are presented In the graphs. The rates are considered significantly different only if the 95% confidence Intervals do not overlap each other. The cover of this monograph illustrates two of the three patterns found In childhood cancer when examining age at diagnosis. The significance of the illustratlon is explained further In the Executive Summary.

Publication Date

1-1-1989

Publisher

Louisiana Tumor Registry

Comments

The Louisiana Tumor Registry can be reached at LTR-info@lsuhsc.edu

Cancer in Louisiana: Volume 5

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