4-Dimensional Intracardiac Echocardiography-Guided Antegrade TAVR Using a Novel CABLE-TAVR Technique

Document Type

Article

Publication Date

5-13-2026

Publication Title

JACC Case Reports

Abstract

Background: An antegrade approach to transcatheter aortic valve replacement (TAVR) has become less common because of the complexity and chance of complication, but use of a large-bore sheath to protect the mitral valve has been described. Case Summary: We present a 75-year-old patient with severe symptomatic aortic stenosis who underwent antegrade TAVR with 4-dimensional intracardiac echocardiography under conscious sedation. We describe a novel technique using an Edwards Commander Delivery System to flex a large-bore sheath across the mitral valve to protect the atrial septum and mitral valve during valve delivery. Discussion: Patients with limited vascular access for retrograde TAVR and who are not candidates for general anesthesia owing to pulmonary disease can undergo antegrade TAVR under conscious sedation and 4-dimensional intracardiac echocardiography guidance. Take-Home Message: Our case illustrates an antegrade approach with a novel technique that may be a suitable alternative to TAVR in high-risk patients who otherwise would not be candidates for aortic valve replacement.

PubMed ID

42126377

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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