Datasets: Crystal Structure and Computational Modeling of the Fab Fragment from a Protective Anti-Ricin Monoclonal Antibody

Authors

Zhiyu Zhao, New Orleans Childrens' Hospital
David Worthylake, LSU Health Sciences Center - New Orleans
Louis LeCour Jr, LSU Health Sciences Center - New Orleans
Grace A. Maresh, New Orleans Childrens' Hospital
Seth H. Pincus, New Orleans Childrens' Hospital

Document Type

Dataset

Publication Date

2-19-2013

Abstract

A. Ribbon structure of the Fab. B. Surface diagram of a potential Ag-binding pocket. C. Electron density map of the CDR loops contoured at 0.5 σ. Color code: light gray (light chain), dark gray (heavy chain), red (CDR L1), yellow (CDR L2), blue (CDR L3), orange (CDR H1), green (CDR H2), purple (CDR H3). Residues lining the pocket are in pink; L chain 96L; H chain 32Y, 33Y, 35N, 47W, 50L, 97A, 98R, 99R, 105L, and 106F. Pocket size: height ∼8 Å, major axis ∼12 Å, minor axis ∼5 Å. Lining the pocket are 6 hydrophobic, and 5 hydrophilic (2 charged) residues.

Comments

Original Article: https://doi.org/10.1371/journal.pone.0052613

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Zhao, Zhiyu; Worthylake, David; LeCour, Louis Jr; Maresh, Grace A.; and Pincus, Seth H., "Datasets: Crystal Structure and Computational Modeling of the Fab Fragment from a Protective Anti-Ricin Monoclonal Antibody" (2013). Data Sets. 104.
https://digitalscholar.lsuhsc.edu/datasets/104