The moderating role of depression in the association between hypertension during pregnancy and birth outcomes

Authors

Yueqi Li, St. Louis University
Jen Jen Chang, St. Louis University
Ruikun Zuo, LSU Health Sciences Center - New OrleansFollow
Hong Xian, St. Louis University
Darcell Scharff, St. Louis University

Document Type

Article

Publication Date

6-20-2023

Publication Title

Hypertension in Pregnancy

Abstract

Objective: Investigate how hypertension during pregnancy (HDP) and depression during pregnancy (DDP) independently and jointly affect infant birth outcomes. Methods: This population-based, retrospective cohort study included a sample of 68,052 women who participated in PRAMS 2016–2018 survey. Poisson regression was used for adjusted relative risks (aRRs). Results: Compared to women without HDP and DDP, aRRs for PTB and LBW among women with both HDP and DDP are 2.04 (95% CI 1.73, 2.42) and 2.84 (95% CI 2.27, 3.56), respectively, albeit lower than the expected joint effect of risk. Conclusion: DDP may modify the association between HDP and PTB, LBW.

PubMed ID

37340557

Volume

42

Issue

1

Recommended Citation

Li, Yueqi; Chang, Jen Jen; Zuo, Ruikun; Xian, Hong; and Scharff, Darcell, "The moderating role of depression in the association between hypertension during pregnancy and birth outcomes" (2023). School of Public Health Faculty Publications. 229.
https://digitalscholar.lsuhsc.edu/soph_facpubs/229