Association Between Treatment For Localized Prostate Cancer And Mental Health Outcomes

Document Type

Article

Publication Date

5-1-2022

Publication Title

Journal of Urology

Abstract

Results: A total of 2,742 men (median [quartiles] age 64 [59e70]) met inclusion criteria. Baseline depressive symptoms, as measured by the CES-D, were low (median 4, quartiles 1e8) without differences between groups. We found no effect of treatment modality on depressive symptoms (p[0.78), though older age, poorer health, being unmarried and baseline CES-D score were associated with declines in mental health. There was no clinically meaningful association between treatment modality and scores for either emotional well-being (p[0.81) or energy/fatigue (p[0.054). Conclusions: This prospective, population-based cohort study of men with localized prostate cancer showed no clinically important differences in mental health outcomes including depressive symptoms, emotional well-being, and energy/fatigue according to the treatment received (surgery, radiotherapy, or surveillance). However, we identified a number of characteristics associated with worse mental health outcomes including: older age, poorer health, being unmarried, and baseline CES-D score which may allow for early identification of patients most at risk of these outcomes following treatment.

First Page

1029

Last Page

1037

PubMed ID

34978488

Volume

207

Issue

5

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