Experimental Studies: Quasi-experimental, Experimental, And Randomized Clinical Trials

Document Type

Book Chapter

Publication Date

1-1-2022

Publication Title

Epidemiology for the Advanced Practice Nurse: A Population Health Approach

Abstract

Experimental research designs provide the epidemiologist with the ability to make statements about relationships, associations, and supportive statements regarding causation. Hypotheses generated through observational research study designs can be tested with an experimental research design. Not all epidemiologic areas of inquiry are adaptable to an experimental research study design. Quasi-experimental research study designs provide an alternative research design to experimental research designs when all the essential elements required for a true experimental study cannot be established within the design. This chapter provides an understanding of quasi-experimental research designs and also of the essential elements of an experimental research design. It helps the reader differentiate the phases of a randomized controlled clinical trial. The chapter discusses the design of a vaccine clinical trial. The goal of the Vaccine Adverse Event Reporting System (VAERS) is to detect possible indicators of adverse events associated with the administration of vaccine.

First Page

153

Last Page

164

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Epidemiology For The Advanced Practice Nurse: A Population Health Approach

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