Multidisciplinary Approach of Musculoskeletal Metastasis| Chapter 23
Document Type
Book Chapter
Publication Date
2-7-2026
Editor
Juan Pretell-Mazzini and Santiago A. Lozano Calderón
Abstract
Tibial metastatic lesions comprise a small proportion of metastatic disease to bone and often signify advanced metastatic disease. These lesions are regularly at risk for pathologic fracture, frequently necessitating operative intervention. Factors influencing decision for surgery include impending or pathological fracture, tumor histology, pain, patient comorbidities, and life expectancy. The goal of surgical treatment is to improve quality of life by improving pain and function and decreasing disease burden. Surgical treatment for tibial shaft metastasis ranges from curettage with or without adjuvants, open or closed reduction and internal fixation, resection with allograft or prosthetic reconstruction, or amputation. Postoperatively, multidisciplinary management is continued with systemic therapy and/or local radiation in addition to anticoagulation, infection prevention, nutritional optimization, and analgesia. This chapter will discuss the epidemiology of metastatic disease involving the tibial shaft and approach to treatment consisting of surgical and nonsurgical indications, preoperative planning, surgical options, and postoperative care.
First Page
349
Last Page
368
Chapter Title
Chapter 23 - Management of Metastatic Disease to the Tibial Shaft
Publisher
Springer Cham
ISBN
[9783032094971, 9783032095008]
Rights
The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2026
Recommended Citation
Williams, Jestin; Khan, Irfan A.; Bloise, Christopher; and Cable, Matthew G., "Multidisciplinary Approach of Musculoskeletal Metastasis| Chapter 23" (2026). School of Medicine Faculty Publications. 4881.
https://digitalscholar.lsuhsc.edu/som_facpubs/4881
10.1007/978-3-032-09498-8_23