Document Type
Article
Publication Date
12-10-2025
Publication Title
Cureus
Abstract
Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare, immunologically driven disorder with a high mortality rate. It is typically diagnosed on the basis of clinical and laboratory criteria. We present the case of a 53-year-old woman with multiple previous hospitalizations for fever of unknown origin and fatigue. Her workup ultimately led to a diagnosis of HLH. We discuss the presentation, diagnostic criteria, and clinical treatment of secondary HLH to guide workup and management for future patients affected by this rare disease.
First Page
e98913
PubMed ID
41523538
Volume
17
Issue
12
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Bartholomew, Alexandra; Connick, Michael; Loehr, Catherine; and Sanne, Shane, "Presentation, Diagnosis, and Acute Treatment of Secondary Hemophagocytic Lymphohistiocytosis: A Case Report" (2025). School of Medicine Faculty Publications. 4428.
https://digitalscholar.lsuhsc.edu/som_facpubs/4428
10.7759/cureus.98913
Included in
Hemic and Immune Systems Commons, Hemic and Lymphatic Diseases Commons, Immune System Diseases Commons, Pathological Conditions, Signs and Symptoms Commons