Document Type
Article
Publication Date
12-13-2025
Publication Title
Cureus
Abstract
Cutaneous metastases are an uncommon but clinically significant manifestation of internal malignancies. We present a rare case of dermal lymphatic carcinomatosis arising from epidermal growth factor receptor (EGFR)-positive lung adenocarcinoma, a presentation that may closely mimic inflammatory dermatoses and indicate therapeutic resistance or disease progression. We describe the clinical course of a 65-year-old woman who developed a violaceous cutaneous metastatic lesion beneath the left breast during treatment for metastatic lung adenocarcinoma. This case highlights the importance of recognizing cutaneous signs as indicators of disease progression and emphasizes the diagnostic challenges and prognostic implications of cutaneous metastases in lung cancer.
First Page
e99152
PubMed ID
41542005
Volume
17
Issue
12
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Hemelt, Sarah A.; Joseph, Jonathan M.; and Culotta, Nicholas, "Dermal Lymphatic Carcinomatosis as a Cutaneous Metastasis From Epidermal Growth Factor Receptor-Positive Lung Adenocarcinoma: A Case Report" (2025). School of Medicine Faculty Publications. 4427.
https://digitalscholar.lsuhsc.edu/som_facpubs/4427
10.7759/cureus.99152
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Dermatology Commons, Medical Cell Biology Commons, Neoplasms Commons, Pathological Conditions, Signs and Symptoms Commons, Respiratory Tract Diseases Commons