Document Type

Article

Publication Date

5-9-2025

Publication Title

JAAD Reviews

Abstract

Neutrophilic alopecias of the scalp - including dissecting cellulitis of the scalp, folliculitis decalvans, and Acne Keloidalis Nuchae - are rare, scarring, inflammatory disorders with overlapping clinical and histopathologic features that present unique diagnostic and therapeutic challenges in pediatric populations. This systematic review synthesizes findings from 35 eligible studies identified through a search of Medical Literature Analysis and Retrieval System Online, Excerpta Medica Database, Central Cochrane Medical Database, Cumulative Index to Nursing and Allied Health Literature, and Web of Science, focusing on treatment modalities and outcomes in children. Patients with dissecting cellulitis of the scalp often present with erythematous, tender scalp nodules with associated patches of alopecia. Systemic antibiotics and retinoids were most commonly used to achieve regression and hair regrowth. Patients with folliculitis decalvans presented with follicular based, erythematous papules with associated crusting and alopecia. Systemic antibiotics led to improvement in inflammation, but often resulted in recurrence. Acne Keloidalis Nuchae, typically affecting postpubertal males of African descent, is managed with a combination of topic retinoids, antibiotics, corticosteroids, and behavioral modification to reduce mechanical irritation. Findings suggest that a combination of systemic, topical, and procedural interventions may yield the most favorable outcomes. This review highlights the gaps in pediatric-specific evidence and the need for further research to optimize therapeutic strategies tailored to this population.

First Page

49

Last Page

61

Volume

5

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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