Document Type
Article
Publication Date
9-12-2025
Publication Title
Cureus
Abstract
Nevus sebaceous of Jadassohn (NS) is a congenital cutaneous hamartoma that typically presents at birth as a plaque on the face, scalp, or neck. While NS is associated with a risk of neoplastic transformation, the majority of secondary tumors are benign, with the most common being trichoblastomas and syringocystadenomas. In this report, we present a rare case of a 63-year-old male with a right parietal scalp NS with a secondary cystic papillary hidradenoma (HP), which is a benign tumor that almost exclusively occurs in the perineal region. Histopathologic examination was consistent with NS, revealing hyperkeratosis, parakeratosis, increased sebaceous glands, ectopic apocrine glands, and anomalous duct sweat gland hyperplasia. The lesion also demonstrated characteristics of HP, a neoplasm that has not been well-documented in association with NS. This case expands understanding of neoplasms that arise within NS and highlights histologic characteristics that differentiate HP from other neoplasms.
First Page
e92156
PubMed ID
41084644
Volume
17
Issue
9
Rights
© 2025, Book et al.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Book, Jordan A.; Prejean, Rosemary; Joseph, Jonathan M.; Culotta, Nicholas; and Haas, Christopher, "Nevus Sebaceous of Jadassohn With Secondary Cystic Papillary Hidradenoma" (2025). School of Medicine Faculty Publications. 4172.
https://digitalscholar.lsuhsc.edu/som_facpubs/4172
10.7759/cureus.92156
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Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, Endocrine System Diseases Commons, Neoplasms Commons