Pregnancy in IBD: keeping mom healthy for a healthy baby

Document Type

Article

Publication Date

7-30-2025

Publication Title

Frontline Gastroenterology

Abstract

Inflammatory bowel disease (IBD) can impact reproductive planning. Achieving disease remission prior to conception is advised, as it can reduce risks for both the mother and the infant. Flare-ups during pregnancy can lead to complications, such as preterm birth. Therefore, managing the disease effectively with the right medications is crucial for optimal outcomes. Most IBD medications (except small molecules and methotrexate) carry minimal risks to the fetus and are safe during breastfeeding, so it is important for individuals to understand the potential dangers of discontinuing treatment and the significance of maintaining remission. Given the rapid change in medical therapies, this review highlights the latest evidence to ensure successful pregnancy outcomes.

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