Document Type

Article

Publication Date

4-9-2025

Publication Title

OTO Open

Abstract

Objective: To assess associations of digital inequity with oropharyngeal cancer (OPC) prognostic and care outcomes in the United States while adjusting for traditional social determinants/drivers of health (SDoH). Study Design: Retrospective cohort study. Setting: United States. Methods: In total, 70,604 patients from 2008 to 2017 were assessed for regression trends in long-term follow-up period, survival, prognosis, and treatment across increasing overall digital inequity, as measured by the Digital Inequity Index (DII). DII is based on 17 census-tract level variables derived from the American Community Survey and Federal Communications Commission. Variables were categorized as infrastructure-access (ie, digital-related variables) or sociodemographic (ie, education, income, and disability status) and weighted-averaged into a composite score. Results: With increasing DII, decreases in length of follow-up (10.22%, 32.9-29.5 months; P < .001) and survival (8.93%, 19-17.3 months; P < .001) were observed. Affordability of internet access displayed the largest influence, followed by device access and internet-service availability. Compared to OPC patients with low digital inequity, high digital inequity was associated with increased odds of diagnosing more than one malignant tumor (odds ratio [OR] 1.01, 95% CI 1.01-1.03; P =.012) and advanced staging (OR 1.01, 95% CI 1.00-1.02; P =.034), while having decreased odds of receiving indicated chemotherapy (OR 0.98, 95% CI 0.97-0.99; P < .001), radiation therapy (OR 0.98, 95% CI 0.97-0.99; P < .001), or primary surgery (OR 0.98, 95% CI 0.97-0.99; P < .001). Conclusion: Digital inequities contribute to detrimental trends in OPC patient care and prognosis in the United States. These findings can inform strategic discourse targeted against the most pertinent disparities in the modern-day environment.

PubMed ID

40206395

Volume

9

Issue

2

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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