Improvement of Hailey-Hailey Disease Following Administration of Dupilumab
Document Type
Article
Publication Date
4-1-2025
Publication Title
Journal of Drugs in Dermatology
Abstract
Hailey-Hailey disease (HHD) is a rare, chronic skin disorder characterized by recurrent inflammatory plaques with painful blisters, erosions, and macerations. We report a case of a 40-year-old female with clinical and pathological findings consistent with HHD. After numerous unsuccessful treatments, including the use of antiseptic washes, topical and oral medications, and injections, the patient was started on dupilumab (300 mg/2 mL syringes every 2 weeks). After 4 months of treatment, there was a clearance of plaques and resolution of pain with only minimal residual erythema. This response was maintained with no reported side effects. Dupilumab may be an effective and safe treatment option for refractory HHD, but it necessitates further research.
First Page
410
Last Page
412
PubMed ID
40196944
Volume
24
Issue
4
Recommended Citation
Kichena, Shravya; Carnicle, Jocelyn; and Haseltine, Mara, "Improvement of Hailey-Hailey Disease Following Administration of Dupilumab" (2025). School of Medicine Faculty Publications. 3701.
https://digitalscholar.lsuhsc.edu/som_facpubs/3701
10.36849/JDD.8060