Hyperuricemia: An Intriguing Connection to Metabolic Syndrome, Diabetes, Kidney Disease, and Hypertension
Document Type
Article
Publication Date
1-25-2024
Publication Title
Current Hypertension Reports
Abstract
Purpose of the Review; Our review explores the epidemiology, physiology, and clinical data surrounding the connection between hyperuricemia and metabolic syndrome, chronic kidney disease, and hypertension. Recent Findings; Compelling physiologic mechanisms have been proposed to explain a causal relationship between hyperuricemia and metabolic syndrome, chronic kidney disease, and hypertension but clinical studies have given mixed results in terms of whether intervening with hyperuricemia using urate-lowering therapy has any beneficial effects for patients with these conditions. Summary; Despite the large amount of research already put into this topic, more randomized placebo-controlled trials are needed to more firmly establish whether a cause-effect relationship exists and whether lowering uric acid levels in patients with these conditions is beneficial.
PubMed ID
38270791
Recommended Citation
Vareldzis, Ramzi; Perez, Annalisa; and Reisin, Efrain, "Hyperuricemia: An Intriguing Connection to Metabolic Syndrome, Diabetes, Kidney Disease, and Hypertension" (2024). School of Medicine Faculty Publications. 2069.
https://digitalscholar.lsuhsc.edu/som_facpubs/2069
10.1007/s11906-024-01295-3