Novel Biodistribution of PSMA Radiotracer in the Uvula of Patients Undergoing PSMA PET/CT

Authors

Phaethon Philbrook, LSU Health Sciences Center - New OrleansFollow
Kelsey R. Casano, Ochsner Health
Daniel J. Lee, UT Southwestern Medical School

Document Type

Article

Publication Date

2-1-2024

Publication Title

Clinical Nuclear Medicine

Abstract

ABSTRACT; Prostate-specific membrane antigen (PSMA) PET/CT is an imaging technique that detects primary and metastatic prostate cancer and evaluates treatment effectiveness. The radioligands for PSMA PET/CT are known to have physiological off-target uptake in various tissues. These include the well-known off-target major and minor salivary glands. We report that, in addition to this location, radioligand uptake can be seen in the uvula, which we suggest is from salivary tissue in this location. PSMA uptake in the uvula is not reported in the literature and is a rare, but normal location for tracer biodistribution in some patients.

First Page

e80

Last Page

e81

PubMed ID

38049963

Volume

49

Issue

2

Recommended Citation

Philbrook, Phaethon; Casano, Kelsey R.; and Lee, Daniel J., "Novel Biodistribution of PSMA Radiotracer in the Uvula of Patients Undergoing PSMA PET/CT" (2024). School of Medicine Faculty Publications. 2065.
https://digitalscholar.lsuhsc.edu/som_facpubs/2065