Novel Predictive and Therapeutic Options for Better Pregnancy Outcome in Frozen Embryo Transfer Cycles
Document Type
Article
Publication Date
6-12-2020
Publication Title
American Journal of Reproductive Immunology
Abstract
Since 1978, in the first decades of in vitro fertilization (IVF), the use of ovarian hyperstimulation allowed for the development and transfer of multiple embryos. As IVF technology improved, the number of multiple pregnancies increased, which led to gradual reduction in the number of embryos that were transferred. Embryo freezing (vitrification) was recommended to allow subsequent transfer if the fresh cycle was unsuccessful. However, experimentation has continued to improve pregnancy outcomes. We discuss here the significance of frozen embryo transfer cycle and the impact of uterine and peripheral immunity dominated by NK cells and regulatory T cells and human chorionic gonadotropin on pregnancy outcome in this innovative mode of IVF therapy.
First Page
1
Last Page
10
PubMed ID
32654307
Volume
85
Issue
4
Publisher
American Society for Reproductive Immunology [Associate Organisation]; Wiley
Recommended Citation
Huber, Warren J.; Sauerbrun-Cutler, May Tal; Krueger, Paula M.; and Sharma, Surendra, "Novel Predictive and Therapeutic Options for Better Pregnancy Outcome in Frozen Embryo Transfer Cycles" (2020). School of Medicine Faculty Publications. 182.
https://digitalscholar.lsuhsc.edu/som_facpubs/182