Platelet Dysfunction Diseases and Conditions: Clinical Implications and Considerations
Document Type
Article
Publication Date
7-29-2020
Publication Title
Advances in Therapy
Abstract
Introduction: Platelet diseases and dysfunction are taught early in medical school to all future physicians. Understanding of the coagulation cascade and hemostatic mechanisms has allowed for targeted pharmacological therapies that have been significantly impactful in clinical practice. Platelets are an early participant in hemostasis physiologically and under pathophysiological states. Methods: A review of literature involving platelet disfunction. Results: Various presentations of platelet diseases and dysfunction challenge clinicians and require a firm understanding of normal platelet function, drugs that mediate or modulate platelet effectiveness, and nonpharmacologic etiologies of platelet diseases and dysfunction with corresponding best practice treatment approaches. Conclusion: This review summarizes normal and abnormal states associated with platelets and treatment strategies.
PubMed ID
32729008
Volume
37(9)
Recommended Citation
Kaye, Alan D.; Jeha, George M.; Moll, Vanessa; Ward, Ceressa T.; Watson, Matthew R.; Wynn, John Thomas 2nd; Hockstein, Maxwell A.; Hall, Kevin M.; Viswanath, Omar; Urits, Ivan; Prabhakar, Amit; and Cornett, Elyse M., "Platelet Dysfunction Diseases and Conditions: Clinical Implications and Considerations" (2020). School of Medicine Faculty Publications. 1673.
https://digitalscholar.lsuhsc.edu/som_facpubs/1673