Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy

Authors

Donnell White, LSU Health Sciences Center - New OrleansFollow
Maryam Sadough Shahmirzadi, LSU Health Sciences Center - New OrleansFollow
Brian Boulmay, LSU Health Sciences Center - New OrleansFollow

Document Type

Article

Publication Date

7-22-2023

Publication Title

Journal of Investigative Medicine High Impact Case Reports

Abstract

Morbidity and mortality associated with radiation-induced secondary malignancies (RISMs) have shifted treatment paradigms to minimize or eliminate radiation from treatment regimens. In this case, a 48-year-old woman was diagnosed with Hodgkin lymphoma (HL) and treated with radiotherapy in 2000. In 2018, she was diagnosed with ductal carcinoma in situ (DCIS) of the right breast and treated with a mastectomy. Soon after, she developed triple-negative invasive ductal carcinoma (IDC) in her reconstructed breast. The patient underwent a left lumpectomy, and pathology showed ER–/PR–/HER2+ IDC. This patient’s multi-phenotypic DCIS and IDC presentation are suspected to be RISM due to her previous HL treatment regimen.

PubMed ID

37480256

Volume

11

Recommended Citation

White, Donnell; Sadough Shahmirzadi, Maryam; and Boulmay, Brian, "Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy" (2023). School of Medicine Faculty Publications. 1289.
https://digitalscholar.lsuhsc.edu/som_facpubs/1289