What Is a Cytokine Storm and Should It Matter to Me?

Authors

Jennifer Simkin, LSUHSC New OrleansFollow
Tierra Strange, LSUHSC New Orleans
Nicholas Leblanc, LSUHSC New OrleansFollow
Jessica C. Rivera, LSUHSC New OrleansFollow

Document Type

Article

Publication Date

1-13-2021

Publication Title

Journal of the American Academy of Orthopaedic Surgeons

Abstract

The recent COVID-19 pandemic has brought attention to cytokines and the phenomenon of cytokine storm into mainstream discussions. In this disease specifically, a cytokine storm overwhelming immune response contributes to the pathophysiology and mortality of the COVID-19 infection. Analogous perturbed immune reactions are experienced in polytrauma patients, compromising local tissue healing while threatening multiple organ systems. The expanding field of osteoimmunology should contribute to the orthopaedic community's understanding of how the immune system response, whether normal or pathologic, affects the whole body outcome of our patients.

PubMed ID

33443384

Volume

29(7)

Recommended Citation

Simkin, Jennifer; Strange, Tierra; Leblanc, Nicholas; and Rivera, Jessica C., "What Is a Cytokine Storm and Should It Matter to Me?" (2021). School of Medicine Faculty Publications. 1225.
https://digitalscholar.lsuhsc.edu/som_facpubs/1225
10.5435/JAAOS-D-20-00805