What Is a Cytokine Storm and Should It Matter to Me?

Document Type

Article

Publication Date

1-13-2021

Publication Title

Journal of the American Academy of Orthopaedic Surgeons

Abstract

The recent COVID-19 pandemic has brought attention to cytokines and the phenomenon of cytokine storm into mainstream discussions. In this disease specifically, a cytokine storm overwhelming immune response contributes to the pathophysiology and mortality of the COVID-19 infection. Analogous perturbed immune reactions are experienced in polytrauma patients, compromising local tissue healing while threatening multiple organ systems. The expanding field of osteoimmunology should contribute to the orthopaedic community's understanding of how the immune system response, whether normal or pathologic, affects the whole body outcome of our patients.

PubMed ID

33443384

Volume

29(7)

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