Authors

Ifeanyi Chukwu O. Onor, LSU Health Sciences Center- New OrleansFollow
Emily K. Johnston, Xavier University of Louisiana College of Pharmacy
Nicole G. Little, Xavier University of Louisiana College of Pharmacy
Lashira M. Hill, Xavier University of Louisiana College of Pharmacy
Oluwabunmi E. Lawal, Xavier University of Louisiana College of Pharmacy
Casey J. Payne, Xavier University of Louisiana College of Pharmacy
Mallory R. Coleman, Xavier University of Louisiana College of Pharmacy
Carolkim H. Huynh, Xavier University of Louisiana College of Pharmacy
Sarah E. Bilbe, Xavier University of Louisiana College of Pharmacy
Ahlam A. Ayyad, Xavier University of Louisiana College of Pharmacy
Kabrea J. Jones, Xavier University of Louisiana College of Pharmacy
Jasmine D. Kinnard, Xavier University of Louisiana College of Pharmacy
Rosanna Dastoori, Xavier University of Louisiana College of Pharmacy
Devinn K. Rolland, Xavier University of Louisiana College of Pharmacy
Amanda S. Miller, Xavier University of Louisiana College of Pharmacy
Robbie A. Beyl, Pennington Biomedical Research Center
Christopher J. Gillard, Xavier University of Louisiana College of PharmacyFollow
John I. Okogbaa, Xavier University of Louisiana College of Pharmacy
Daniel F. Sarpong, Xavier University of Louisiana College of Pharmacy
Rim M. Hadgu, Midwestern University Glendale
Amne Borghol, Xavier University
Samuel C. Okpechi, LSU Health Sciences Center- New OrleansFollow
Mihran V. Naljayan, LSU Health Sciences Center- New OrleansFollow
Shane E. Sanno, LSU Health Sciences Center- New Orleans
Shane G. Guillory, LSU Health Sciences Center- New OrleansFollow

Document Type

Article

Publication Date

6-1-2021

Publication Title

Journal of Clinical Hypertension

Abstract

Although the role of magnesium in blood pressure has been well studied among hypertensive patients, no study has explored the role of magnesium in hypertensive crises. The primary objective of this study is to evaluate the differences in serum magnesium levels between hypertensive crises patients and matched controls (age-, sex-, race-, and diabetes-matched) in a 1:1 random match. This study is a single-center, retrospective, chart review, case-control study of patients with hypertensive crises (case group) and patients without hypertensive crises (control group). Patients were included in the case group if they were 18 years of age or older with hypertensive crises and have a documented magnesium level. The control group patients were required to be 18 years of age or older, have no diagnosis of hypertensive crises, and have a documented magnesium level. The primary outcome of the study was to compare the mean serum magnesium in patients with hypertensive crises versus patients without hypertensive crises. Three hundred and fifty-eight patients were included in the study: 179 patients in both the case group and control group. The primary outcome results showed that serum magnesium concentration was not significantly different between the case group (1.89 ± 0.29 mg/dl) and control group (1.90 ± 0.31 mg/dl) (p =.787). This study found no significant difference in serum magnesium levels in patients with hypertensive crises compared to a random matched control group. Larger observational or experimental studies may be useful to evaluate the effect of magnesium on blood pressure in hypertensive crises.

First Page

1229

Last Page

1238

PubMed ID

33963802

Volume

23

Issue

6

Publisher

Wiley; Wiley Periodicals

File Format

pdf

File Size

440 KB

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