Document Type
Article
Publication Date
6-1-2021
Publication Title
Journal of Clinical Hypertension
Abstract
Although the role of magnesium in blood pressure has been well studied among hypertensive patients, no study has explored the role of magnesium in hypertensive crises. The primary objective of this study is to evaluate the differences in serum magnesium levels between hypertensive crises patients and matched controls (age-, sex-, race-, and diabetes-matched) in a 1:1 random match. This study is a single-center, retrospective, chart review, case-control study of patients with hypertensive crises (case group) and patients without hypertensive crises (control group). Patients were included in the case group if they were 18 years of age or older with hypertensive crises and have a documented magnesium level. The control group patients were required to be 18 years of age or older, have no diagnosis of hypertensive crises, and have a documented magnesium level. The primary outcome of the study was to compare the mean serum magnesium in patients with hypertensive crises versus patients without hypertensive crises. Three hundred and fifty-eight patients were included in the study: 179 patients in both the case group and control group. The primary outcome results showed that serum magnesium concentration was not significantly different between the case group (1.89 ± 0.29 mg/dl) and control group (1.90 ± 0.31 mg/dl) (p =.787). This study found no significant difference in serum magnesium levels in patients with hypertensive crises compared to a random matched control group. Larger observational or experimental studies may be useful to evaluate the effect of magnesium on blood pressure in hypertensive crises.
First Page
1229
Last Page
1238
PubMed ID
33963802
Volume
23
Issue
6
Publisher
Wiley; Wiley Periodicals
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Recommended Citation
Onor, Ifeanyi Chukwu O.; Johnston, Emily K.; Little, Nicole G.; Hill, Lashira M.; Lawal, Oluwabunmi E.; Payne, Casey J.; Coleman, Mallory R.; Huynh, Carolkim H.; Bilbe, Sarah E.; Ayyad, Ahlam A.; Jones, Kabrea J.; Kinnard, Jasmine D.; Dastoori, Rosanna; Rolland, Devinn K.; Miller, Amanda S.; Beyl, Robbie A.; Gillard, Christopher J.; Okogbaa, John I.; Sarpong, Daniel F.; Hadgu, Rim M.; Borghol, Amne; Okpechi, Samuel C.; Naljayan, Mihran V.; Sanno, Shane E.; and Guillory, Shane G., "Evaluation of Serum Magnesium Differences in Hypertensive Crises and Control Patients: A Randomly Matched Case-Control Study" (2021). School of Medicine Faculty Publications. 109.
https://digitalscholar.lsuhsc.edu/som_facpubs/109
10.1111/jch.14244
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File Size
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