Authors

Ifeanyi Chukwu O. Onor, LSU Health Sciences Center- New OrleansFollow
Rose M. Duchane, Xavier University of Louisiana College of Pharmacy
Casey J. Payne, Xavier University of Louisiana College of Pharmacy
Hannah Naquin Lambert, Xavier University of Louisiana College of Pharmacy
De Maurian M. Mitchner, Xavier University of Louisiana College of Pharmacy
Robbie A. Beyl, Pennington Biomedical Research Center
Anh T. Nguyen, Xavier University of Louisiana College of Pharmacy
Sarah E. Bilbe, Xavier University of Louisiana College of Pharmacy
Andrea Arriaga White, Xavier University of Louisiana College of Pharmacy
Mariah W. Johnson, Xavier University of Louisiana College of Pharmacy
Amber I. Faciane, Xavier University of Louisiana College of Pharmacy
Emmanuel Kouagou, Xavier University of Louisiana College of Pharmacy
Stephanie A. Hymel, Xavier University of Louisiana College of Pharmacy
Bria M. Wates, Xavier University of Louisiana College of Pharmacy
Asia D. Sanders, Xavier University of Louisiana College of Pharmacy
Phillip C.B. Vo, Xavier University of Louisiana College of Pharmacy
Jordan D. Bates, Xavier University of Louisiana College of Pharmacy
Raven J. Spooner, Xavier University of Louisiana College of Pharmacy
Christopher J. Gillard, Xavier University of Louisiana College of Pharmacy
John I. Okogbaa, Xavier University of Louisiana College of Pharmacy
Daniel F. Sarpong, Xavier University
Rim M. Hadgu, Midwestern University
Samuel C. Okpechi, LSU Health Sciences Center- New OrleansFollow
Gabriel I. Onor, Brown University
Michael C. Okoronkwo, LSU Health Sciences Center- New OrleansFollow
Mihran V. Naljayan, LSU Health Sciences Center- New OrleansFollow
Shane G. Guillory, LSU Health Sciences Center- New OrleansFollow
Shane E. Sanne, LSU Health Sciences Center- New OrleansFollow

Document Type

Article

Publication Date

9-1-2021

Publication Title

Journal of Clinical Hypertension

Abstract

The role of calcium in blood pressure has been widely studied among hypertensive patients; however, no study has explored the role of calcium in hypertensive crises. The primary objective of this study is to evaluate the differences in serum calcium levels between hypertensive crises patients and a 1:1 random matched controls (age-, sex-, race-, diabetes, and body mass index matched). This study is a single-center, retrospective, chart review, case-control study of patients with hypertensive crises (case group) and patients without hypertensive crises (control group). Patients were included in the case group if they were 18 years of age or older with hypertensive crises and have a documented calcium level. The control group patients were required to be 18 years of age or older, have a documented calcium level, and have no diagnosis of hypertensive crises. The primary outcome of the study was to compare the mean serum calcium in patients with hypertensive crises vs patients without hypertensive crises. Five hundred and sixty-six patients were included in the study: 283 patients in both the case group and control group. The primary outcome results showed that serum calcium concentration was not significantly different between the case group (8.99 ± 0.78 mg/dL) and control group (8.96 ± 0.75 mg/dL) (P =.606). This study found no significant difference in serum calcium levels in patients with hypertensive crises compared to a random matched control group. Larger observational or experimental studies may be useful to evaluate the effect of calcium on blood pressure in hypertensive crises.

First Page

1767

Last Page

1775

PubMed ID

34291559

Volume

23

Issue

9

Publisher

Wiley; Wiley Periodicals

File Format

pdf

File Size

1090 KB

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