Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting

Authors

Rachel H. McMahan, University of Colorado School of Medicine
Paige Anton, University of Colorado Anschutz Medical Campus
Leon G. Coleman, UNC School of Medicine
Gail A.M. Cresci, Cleveland Clinic Foundation
Fulton T. Crews, UNC School of Medicine
Kathryn M. Crotty, Emory University
Marisa E. Luck, Loyola University Stritch School of Medicine
Patricia E. Molina, LSU Health Sciences Center - New OrleansFollow
Vidula Vachharajani, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Joanne Weinberg, University of British Columbia, Faculty of Medicine
Samantha M. Yeligar, Emory University
Mashkoor A. Choudhry, Loyola University Stritch School of Medicine
Rebecca L. McCullough, University of Colorado Anschutz Medical Campus
Elizabeth J. Kovacs, University of Colorado School of Medicine

Document Type

Article

Publication Date

5-30-2023

Publication Title

Alcohol

Abstract

On October 26th, 2022 the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held as a satellite symposium at the annual meeting of the Society for Leukocyte Biology in Hawaii. The 2022 meeting focused broadly on the immunological consequences of acute, chronic, and prenatal alcohol exposure and how these contribute to damage in multiple organs and tissues. These included alcohol-induced neuroinflammation, impaired lung immunity, intestinal dysfunction, and decreased anti-microbial and anti-viral responses. In addition, research presented covered multiple pathways behind alcohol-induced cellular dysfunction, including mitochondrial metabolism, cellular bioenergetics, gene regulation, and epigenetics. Finally, the work presented highlighted potential biomarkers and novel avenues of treatment for alcohol-induced organ damage.

First Page

57

Last Page

63

PubMed ID

37061143

Volume

110

Recommended Citation

McMahan, Rachel H.; Anton, Paige; Coleman, Leon G.; Cresci, Gail A.M.; Crews, Fulton T.; Crotty, Kathryn M.; Luck, Marisa E.; Molina, Patricia E.; Vachharajani, Vidula; Weinberg, Joanne; Yeligar, Samantha M.; Choudhry, Mashkoor A.; McCullough, Rebecca L.; and Kovacs, Elizabeth J., "Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting" (2023). School of Graduate Studies Faculty Publications. 83.
https://digitalscholar.lsuhsc.edu/sogs_facpubs/83
10.1016/j.alcohol.2023.04.002