Use of Tisseel, a Fibrin Sealant, for Particulate Graft Stabilization

Authors

Michael S. Block, LSU Health Sciences Center - New OrleansFollow
Michelle Zoccolillo, LSU Health Sciences Center - New Orleans

Document Type

Article

Publication Date

2-22-2020

Publication Title

Journal of Oral and Maxillofacial Surgery

Abstract

One clinical problem when augmenting a narrow or vertically deficient ridge is maintenance of the graft position during the immediate healing phase and preservation of the augmentation over time. The use of Tisseel (Baxter, Deerfield, IL), a fibrin sealant product, to stabilize particulate grafts, has been reported, and we have reviewed its use. Fibrinogen is converted to fibrin and forms a fibular network that binds the particulate graft. A protease inhibitor is included, which prevents lysis of the coagulum for at least 2 weeks and allows for fibrous ingrowth and graft stabilization. We have reviewed the reported data and included 2 case reports to demonstrate the use of Tisseel.

First Page

1674

Last Page

1681

PubMed ID

32192927

Volume

78

Issue

10

Recommended Citation

Block, Michael S. and Zoccolillo, Michelle, "Use of Tisseel, a Fibrin Sealant, for Particulate Graft Stabilization" (2020). School of Dentistry Faculty Publications. 88.
https://digitalscholar.lsuhsc.edu/sod_facpubs/88