Intraoperative Transfusion of Fresh Frozen Plasma is Associated with Increased Hospital Length of Stay

Document Type

Abstract

Location

Virtual

Start Date

24-4-2026 9:00 AM

End Date

24-4-2026 3:00 PM

Description

Introduction Procedure specific pathways for cardiac surgery promote faster recovery with fewer complications.1,2 However, blood product administration hinders recovery.3 We examined the role of intraoperative fresh frozen plasma administration on hospital length of stay and on the disposition status at hospital discharge in adults following cardiovascular surgery. Methods Following Institutional Review Board approval, patient characteristics, need for intraoperative transfusion of fresh frozen plasma, hospital length of stay, and the disposition status at hospital discharge were the measures of interest in 1480 adult patients undergoing cardiovascular surgery. Measures of effect size were used for clinical assessments. Key analyses included 95% confidence intervals (CI).4 Results Baseline patient characteristics are shown in Table 1. An increase in hospital length of stay was observed in patients receiving intraoperative transfusion of fresh frozen plasma (Table 2). Risk differences in the need for advanced care at hospital discharge were calculated in this patient population. An increased risk difference of 20.6% CI 14.3-26.9% was detected in the need for advance care at hospital discharge following intraoperative administration of fresh frozen plasma (Fig. 1). Conclusions These results suggest that the intraoperative administration of fresh frozen plasma increases hospital length of stay and increases the need for advanced post-hospital care.

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Apr 24th, 9:00 AM Apr 24th, 3:00 PM

Intraoperative Transfusion of Fresh Frozen Plasma is Associated with Increased Hospital Length of Stay

Virtual

Introduction Procedure specific pathways for cardiac surgery promote faster recovery with fewer complications.1,2 However, blood product administration hinders recovery.3 We examined the role of intraoperative fresh frozen plasma administration on hospital length of stay and on the disposition status at hospital discharge in adults following cardiovascular surgery. Methods Following Institutional Review Board approval, patient characteristics, need for intraoperative transfusion of fresh frozen plasma, hospital length of stay, and the disposition status at hospital discharge were the measures of interest in 1480 adult patients undergoing cardiovascular surgery. Measures of effect size were used for clinical assessments. Key analyses included 95% confidence intervals (CI).4 Results Baseline patient characteristics are shown in Table 1. An increase in hospital length of stay was observed in patients receiving intraoperative transfusion of fresh frozen plasma (Table 2). Risk differences in the need for advanced care at hospital discharge were calculated in this patient population. An increased risk difference of 20.6% CI 14.3-26.9% was detected in the need for advance care at hospital discharge following intraoperative administration of fresh frozen plasma (Fig. 1). Conclusions These results suggest that the intraoperative administration of fresh frozen plasma increases hospital length of stay and increases the need for advanced post-hospital care.