Neonatal Survivability following Previable PPROM after Hospital Readmission for Intervention
Document Type
Article
Publication Date
10-1-2020
Publication Title
AJP reports
Abstract
To describe our hospital's experience following expectant management of previable preterm prelabor rupture of membranes (pPPROM). Retrospective review of neonatal survival and maternal and neonatal outcomes of pPPROM cases between 2012 and 2019 at a tertiary referral center in South Central Louisiana. Regression analyses were performed to identify predictors of neonatal survival. Of 81 cases of pPPROM prior to 23 weeks gestational age (WGA), 23 survived to neonatal intensive care unit discharge (28.3%) with gestational age at rupture ranging from 18 to 22 WGA. Increased latency (adjusted odds ratio [aOR] = 1.30, 95% confidence interval [CI] = 1.11, 1.52) and increased gestational age at rupture (aOR = 1.62, 95% CI = 1.19, 2.21) increased the probability of neonatal survival. Antibiotics prior to delivery were associated with increased latency duration (adjusted hazard ratio = 0.55, 95% CI = 0.42, 0.74). Neonatal survival rate following pPPROM was 28.3%. Later gestational age at membrane rupture and increased latency periods are associated with increased neonatal survivability. Antibiotic administration following pPPROM increased latency duration.
First Page
e395
Last Page
e402
DOI
10.1055/s-0040-1721421
Recommended Citation
LeMoine, Felicia; Moore, Robert C.; Chapple, Andrew; Moore, Ferney A.; and Sutton, Elizabeth, "Neonatal Survivability following Previable PPROM after Hospital Readmission for Intervention" (2020). LSU-LCMC Cancer Center Faculty Publications. 37.
https://digitalscholar.lsuhsc.edu/llcc_facpubs/37
10.1055/s-0040-1721421