MUTUALLY PULSE-COUPLED NEURONS THAT DO NOT SYNCHRONIZE IN ISOLATION CAN SYNCHRONIZE VIA RECIPROCAL COUPLING WITH ANOTHER NEURAL POPULATION

Document Type

Presentation

Start Date

22-10-2010 3:00 PM

End Date

22-10-2010 4:30 PM

Description

We examine two reciprocally coupled clusters of pulse-coupled oscillatory neurons. Neurons within each cluster are presumed to be identical and identically coupled but not necessarily identical to neurons in the other cluster. We construct a discrete map using Phase Response Curves (PRCs) for a firing pattern in which the neurons within each cluster are synchronized but the two clusters fire out of phase with respect to each other. We extend this map to include a perturbation of a single neuron within one cluster and linearize about the fixed point of the original map. We derive expressions that give stability of the phase-locked cluster solution using only the slopes of the PRC at the locking points. We give an example of a cluster of inhibitory Type II excitable neurons that cannot synchronize in isolation because the absolute value of the eigenvalue that determines synchrony in the isolated cluster is greater than one. The reciprocal coupling with another cluster scales this eigenvalue such that it becomes less than one, thus guaranteeing stability. These results suggest a mechanism by which local synchronization can be induced through reciprocal coupling between brain regions via the feedback loop.

Comments

See abstract book page 49

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Oct 22nd, 3:00 PM Oct 22nd, 4:30 PM

MUTUALLY PULSE-COUPLED NEURONS THAT DO NOT SYNCHRONIZE IN ISOLATION CAN SYNCHRONIZE VIA RECIPROCAL COUPLING WITH ANOTHER NEURAL POPULATION

We examine two reciprocally coupled clusters of pulse-coupled oscillatory neurons. Neurons within each cluster are presumed to be identical and identically coupled but not necessarily identical to neurons in the other cluster. We construct a discrete map using Phase Response Curves (PRCs) for a firing pattern in which the neurons within each cluster are synchronized but the two clusters fire out of phase with respect to each other. We extend this map to include a perturbation of a single neuron within one cluster and linearize about the fixed point of the original map. We derive expressions that give stability of the phase-locked cluster solution using only the slopes of the PRC at the locking points. We give an example of a cluster of inhibitory Type II excitable neurons that cannot synchronize in isolation because the absolute value of the eigenvalue that determines synchrony in the isolated cluster is greater than one. The reciprocal coupling with another cluster scales this eigenvalue such that it becomes less than one, thus guaranteeing stability. These results suggest a mechanism by which local synchronization can be induced through reciprocal coupling between brain regions via the feedback loop.