Examination Date

5-2024

Degree

Thesis

Degree Program

Master of Science (MS) Biostatistics

Examination Committee

Xiao-Cheng wu, PhD; Hui-Yi Lin, PhD

Abstract

Studies have shown that Non-Hispanic Black (NHB) populations have increased COVID-19 related deaths than Non-Hispanic White (NHW) patients. Moreover, a person’s cancer status has also been identified as a factor increasing the risk of death from COVID-19. Previous research has demonstrated racial disparities in COVID-19 hospitalization, and has used mediation analyses to explore potential explanatory factors, such as chronic diseases. In this study, we investigated COVID-19 related deaths amongst cancer patients to assess the presence of racial disparity, and to explore potential mediators that could explain this relationship. NHB and NHW cancer patients who died of COVID-19 were identified for analysis. Two mediation analyses were conducted—one using the Charlson Comorbidity Index and the other using individual diseases as potential mediators. Findings revealed that Charlson Comorbidity Index mediated the relationship between race and the risk of COVID-19 related death. Specifically, renal disease emerged as the top chronic disease contributing to the racial difference.

Download

Share

COinS