Additional file 4 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data
Document Type
Dataset
Publication Date
2022
Publication Title
Figshare
Abstract
Additional file 4. Concentration and forest plots for each individual immune mediator. Concentration plots - Each symbol shows the concentration of the indicated immune mediator in a single sample. Each study is plotted separately. Lines connect samples from the same participant; in some cases participants provided multiple samples in the same phase, in which case multiple symbols within the same phase may be connected. Pale grey symbols are below the lower limit of detection and are assigned the value of half the lower limit of detection. Forest plots - Each row represents a different study, with the vertical line at the middle of each square indicating the mean and the horizontal line indicating the 95% confidence interval. Positive numbers indicate higher concentrations during the luteal phase (compared to the follicular phase), while negative numbers indicate lower concentrations during the luteal phase (compared to the follicular phase). The size of the squares is proportional to how heavily the study is weighted in the meta-analysis. The center of the diamond and the vertical dotted line indicates the meta-effect as determined by the random effects model. The width of the diamond indicates the 95% confidence interval of the meta-effect. A narrow diamond indicates small confidence intervals, a wide diamond indicates large confidence intervals. TE, treatment effect (log2-pg/mL of the luteal phase minus log2-pg/mL of the follicular phase); seTE, standard error of the treatment effect; 95%-CI, 95% confidence interval around the treatment effect; Weight, the percentage of the meta-estimate contributed by each study.
DOI
10.6084/m9.figshare.21275960.v1
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Hughes, Sean M.; Levy, Claire N.; Katz, Ronit; Lokken, Erica M.; Anahtar, Melis N.; Hall, Melissa Barousse; Bradley, Frideborg; Castle, Philip E.; Cortez, Valerie; Doncel, Gustavo F.; Fichorova, Raina; Fidel, Paul L.; Fowke, Keith R.; Francis, Suzanna C.; Ghosh, Mimi; Hwang, Loris Y.; Jais, Mariel; Jespers, Vicky; Joag, Vineet; Kaul, Rupert; Kyongo, Jordan; Lahey, Timothy; Li, Huiying; Makinde, Julia; McKinnon, Lyle R.; Moscicki, Anna-Barbara; Novak, Richard M.; Hladik, Florian; Across the Menstrual Cycle, The Consortium for Assessing; and al., et., "Additional file 4 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data" (2022). Data Sets. 20.
https://digitalscholar.lsuhsc.edu/datasets/20
10.6084/m9.figshare.21275960.v1
Comments
Original Article:
https://doi.org/10.1186/s12916-022-02532-12