Epidemiology for the Advanced Practice Nurse: A Population Health Approach
Cohort study designs are a population-based observational epidemiologic study. Cohort studies evolve over time as diagnostic and medical science advances; for example, improved diagnostic screening and testing methods will be integrated into a cohort study design as they are developed or improved. This chapter describes an epidemiologic cohort study design, differentiates a prospective and retrospective cohort study design, and shows how to calculate a risk ratio and rate ratio. Cohort study designs can be developed with an integration of other study designs. A case-control study design can be nested into a cohort study design. In addition, there can be a nested case-control study design within a cohort study design with matching of cases and controls to account for confounding variables. Other study designs can be combined with or integrated into a cohort study design as a strategy to increase internal and external validity of the research study design.
Porche, Demetrius J., "Cohort Studies" (2022). School of Nursing Faculty Publications. 52.