Presentation Date
13-10-2022 12:00 AM
Description
Introduction. African-American (B) youth with Type 1 Diabetes consistently have higher A1c than White (W) patients, even when using open-loop insulin pumps. AHCL technology utilizes glucose sensor data to guide automatic adjustments of insulin by the pump throughout the day to mitigate hyper and hypoglycemia. Potentially AHCL could reduce or eliminate disparity in glycemic outcome in high-risk patient populations Methods and Results. We performed a retrospective chart review of clinic patients who were using Tandem Control IQ (CIQ) AHCL system. Patients were trained in AHCL use by the manufacturer’s representative and then followed routinely in diabetes clinic at the Children’s Hospital of New Orleans (n=62). Data was excerpted from patient eMR and t-connect data bases. Patients were included in the analysis if they had used CIQ for more than 120 days and had officially self-identified in the eMR as either non-Hispanic White (W) or non-Hispanic Black/African-American (B) and had paired data for HbA1c and glucose sensor data at the last clinic visit. Sensor/system data stats were assessed for the 30 days prior to clinic visit. Eight patients self-identified as B and Twenty-nine as W. There was a statistical and clinically significant reduction in A1c (-1.2%±1.6, p=0.0007) for W patients but not B (-0.09±1.6, p=NS) with AHCL use. B patients had higher A1c and sensor Mean Blood Glucose (MBG) with lower percent time in use (TIU) during AHCL mode than W patients. The percent insulin bolus, basal, units of insulin per kg per day, percent glucoses/dL were not different between groups. Overall, latest A1c was significantly correlated with sMBG (r=0.75, p
Recommended Citation
Christakis, Nicholas; Gioe, Marcella; and Chalew, Stuart, "Racial Disparity in Glycemic Outcome During Real World Use of an Advanced Hybrid Closed Loop System (AHCL) Among Youth with Type 1 Diabetes (T1D)" (2022). Medical Research Day. 92.
https://digitalscholar.lsuhsc.edu/sommrd/2022MRD/Posters/92
Included in
Racial Disparity in Glycemic Outcome During Real World Use of an Advanced Hybrid Closed Loop System (AHCL) Among Youth with Type 1 Diabetes (T1D)
Introduction. African-American (B) youth with Type 1 Diabetes consistently have higher A1c than White (W) patients, even when using open-loop insulin pumps. AHCL technology utilizes glucose sensor data to guide automatic adjustments of insulin by the pump throughout the day to mitigate hyper and hypoglycemia. Potentially AHCL could reduce or eliminate disparity in glycemic outcome in high-risk patient populations Methods and Results. We performed a retrospective chart review of clinic patients who were using Tandem Control IQ (CIQ) AHCL system. Patients were trained in AHCL use by the manufacturer’s representative and then followed routinely in diabetes clinic at the Children’s Hospital of New Orleans (n=62). Data was excerpted from patient eMR and t-connect data bases. Patients were included in the analysis if they had used CIQ for more than 120 days and had officially self-identified in the eMR as either non-Hispanic White (W) or non-Hispanic Black/African-American (B) and had paired data for HbA1c and glucose sensor data at the last clinic visit. Sensor/system data stats were assessed for the 30 days prior to clinic visit. Eight patients self-identified as B and Twenty-nine as W. There was a statistical and clinically significant reduction in A1c (-1.2%±1.6, p=0.0007) for W patients but not B (-0.09±1.6, p=NS) with AHCL use. B patients had higher A1c and sensor Mean Blood Glucose (MBG) with lower percent time in use (TIU) during AHCL mode than W patients. The percent insulin bolus, basal, units of insulin per kg per day, percent glucoses/dL were not different between groups. Overall, latest A1c was significantly correlated with sMBG (r=0.75, p
Comments
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