Presentation Date

13-10-2022 12:00 AM


Introduction: Nearly 300,000 Americans currently live with a spinal cord injury with 17,500 new spinal cord injuries occurring yearly. The early clinical management of traumatic spinal cord injury (TSCI) is crucial to the impact on patient outcomes. Adequate blood pressures are necessary in maintaining perfusion to injured neural tissue and preventing secondary ischemic insult. In 2013, the American Association of Neurologic Surgeons recommended that mean arterial blood pressure (MAP) be maintained between 85-90 mmHg for seven days after TSCI. This guideline was initially supported by several case series and it is a Class III recommendation. However, 100% adherence to these guidelines is rarely accomplished in practice. Previous studies have demonstrated difficulty with MAP goal compliance in this patient population. Objective: The objective of this study was to determine physician compliance with MAP guidelines and neurologic function in TSCI patients. Methods: A retrospective chart review of consecutive adult patients with TSCIs occurring from July 2012 to August 2021 who presented to an urban Level 1 trauma center was performed. Electronic medical records were used to identify trauma patients and to obtain demographics and patient outcomes. Daily MAPs were collected for seven days post-admission. Compliance was quantified as the ability to successfully maintain an average weekly MAP >85 whereas noncompliance is quantified as an average weekly MAP0.05), and spinal surgery (p=0.2). Patients in the non-compliance group were more likely to be female (p=0.001) and had a significantly longer ICU length of stay (p=0.01). There was no significant difference in ASIA score improvement at the time of discharge (p=0.7) and at initial clinic followup (p=0.9). Conclusions: In this study, compliance with current guidelines did not show an association with neurologic outcome. The specific patient population in the non-compliance group had a longer ICU length of stay and were more likely to be female. Future studies will focus on the further elucidating risk factors for non-compliance with MAP goals and how this plays a role in postMAP protocol neurologic improvement.

Included in

Surgery Commons


Oct 13th, 12:00 AM

Impact of Mean Arterial Blood Pressure Compliance on Neurologic Outcomein Patients with Traumatic Spinal Cord Injuries