The Prognostic Implications of Tetraploidy/Near-Tetraploidy in Acute Myeloid Leukemia: A Case Series and Systematic Review of the Literature
Location
Virtual
Presentation Date
26-10-2020 10:00 AM
End Date
30-10-2020 3:00 PM
Description
Clinically significant fat necrosis is a common and significant complication of autologous breast reconstruction. Additional operation is typically required to exclude residual or re-emergence of malignancy, to improve cosmesis, and relieve aggravating symptoms such as pain and impaired mobility. To investigate the incidence of operable fat necrosis and identify potential contributing factors, the authors examined the effects of single vs. stacked perforator free flap use in autologous breast reconstruction and subsequent development of clinically significant fat necrosis. The authors conducted a retrospective review of all patients undergoing perforator free flap breast reconstruction from January 2009 to November 2019. 460 free flaps were analyzed for factors contributing to the formation of fat necrosis including stacked vs single flap reconstruction, flap weight, patient characteristics and patient comorbidities. Retrospective analysis revealed no relationship between the use of single vs stacked perforator flaps on the formation of fat necrosis. However, an association was found between flap weight and the formation of fat necrosis, separate from the use of single or stacked flaps. Further research is needed to discern the occurrence of fat necrosis in the separate flaps that comprise a stacked flap reconstruction to more accurately compare fat necrosis rates to single flap reconstruction.
Recommended Citation
Nachabe, Adeem; Xie, John; Hathaway, Lindsey J.; Farah, Bachir; Collins, Julie M.; Saba, Nakhle; and Safah, Hana, "The Prognostic Implications of Tetraploidy/Near-Tetraploidy in Acute Myeloid Leukemia: A Case Series and Systematic Review of the Literature" (2020). Medical Student Research Poster Symposium. 42.
https://digitalscholar.lsuhsc.edu/sommrd/2020/virtual/42
The Prognostic Implications of Tetraploidy/Near-Tetraploidy in Acute Myeloid Leukemia: A Case Series and Systematic Review of the Literature
Virtual
Clinically significant fat necrosis is a common and significant complication of autologous breast reconstruction. Additional operation is typically required to exclude residual or re-emergence of malignancy, to improve cosmesis, and relieve aggravating symptoms such as pain and impaired mobility. To investigate the incidence of operable fat necrosis and identify potential contributing factors, the authors examined the effects of single vs. stacked perforator free flap use in autologous breast reconstruction and subsequent development of clinically significant fat necrosis. The authors conducted a retrospective review of all patients undergoing perforator free flap breast reconstruction from January 2009 to November 2019. 460 free flaps were analyzed for factors contributing to the formation of fat necrosis including stacked vs single flap reconstruction, flap weight, patient characteristics and patient comorbidities. Retrospective analysis revealed no relationship between the use of single vs stacked perforator flaps on the formation of fat necrosis. However, an association was found between flap weight and the formation of fat necrosis, separate from the use of single or stacked flaps. Further research is needed to discern the occurrence of fat necrosis in the separate flaps that comprise a stacked flap reconstruction to more accurately compare fat necrosis rates to single flap reconstruction.
Comments
Mentor: Hana Safah, MD (Tulane University School of Medicine, Department of Internal Medicine, Section of Hematology and Oncology)