A Novel Technique for Radiographic Diagnosis of Sarcopenia that Accurately Predicts Postoperative Complications in Lower Extremity Free Flap Patients

Authors

Suma S. Maddox, LSU Health Sciences Center- New Orleans
Patrick A. Palines, LSU Health Sciences Center- New OrleansFollow
Ryan D. Hoffman, LSU Health Sciences Center- New OrleansFollow
Denise M. Danos, LSU Health Sciences Center- New OrleansFollow
Daniel J. Womac, LSU Health Sciences Center- New OrleansFollow
Charles T. Tuggle, LSU Health Sciences Center- New OrleansFollow
Mark W. Stalder, LSU Health Sciences Center- New OrleansFollow

Document Type

Article

Publication Date

11-1-2021

Publication Title

Journal of Reconstructive Microsurgery

Abstract

Background  Sarcopenia is linked to poor outcomes throughout the surgical literature and can be assessed on preoperative imaging to potentially aid in risk stratification. This study examined the effects of sarcopenia on surgical morbidity following lower extremity (LE) reconstruction, and also compared two methods of assessment, one of which is novel (ellipse method). Methods  A retrospective cohort study of 50 patients receiving free flap-based reconstruction of the LE was performed. Bilateral psoas density and area were quantified at L4 through tracing (traditional method) and encircling (ellipse method) to calculate Hounsfield unit average calculation (HUAC). Logistic regression and receiving operator curve analysis for the primary outcome of any postoperative complication was used to determine HUAC cutoffs (≤ 20.7 vs. ≤ 20.6) for sarcopenia. Risk of complications associated with sarcopenia was evaluated using Fisher's exact tests. Results  Twelve patients (24%) met criteria for sarcopenia via the traditional method and 16 (32%) via the ellipse method. By both methods, sarcopenic patients were older and more often female and diabetic. These patients also had higher American Society of Anesthesiologists scores and lower serum prealbumin levels. The ellipse method was found to be more accurate, sensitive, and specific than the traditional method in predicting postoperative morbidity (p = 0.009). Via the ellipse method, sarcopenic patients were at higher risk for any complication (p = 0.002) and were at a higher risk for a deep vein thrombus or pulmonary embolism via the traditional method (p = 0.047). Conclusion  Sarcopenia is associated with greater pre- and postoperative morbidity in LE reconstruction. The novel ellipse method is a simplified and accurate method of assessing sarcopenia that can be easily performed in the clinical setting.

First Page

744

Last Page

752

PubMed ID

33853127

Volume

37

Issue

9

Publisher

Thieme Gruppe

Recommended Citation

Maddox, Suma S.; Palines, Patrick A.; Hoffman, Ryan D.; Danos, Denise M.; Womac, Daniel J.; Tuggle, Charles T.; and Stalder, Mark W., "A Novel Technique for Radiographic Diagnosis of Sarcopenia that Accurately Predicts Postoperative Complications in Lower Extremity Free Flap Patients" (2021). School of Medicine Faculty Publications. 362.
https://digitalscholar.lsuhsc.edu/som_facpubs/362