Treatment and Management of Autoimmune Neuropathies

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Neuromuscular Disorders: Treatment and Management


The autoimmune neuropathies represent an important category of the peripheral neuropathies. We need to recognize the potential implications of autoimmune neurology-a new subspecialty in neurology that has truly launched. We review the clinical patterns, diagnostic paradigms, etiopathogenesis, and therapeutic strategies of autoimmune neuropathies such as Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy, immunoglobulin M paraproteinemic neuropathy, nodopathies, as well as immune neuropathies associated with other systemic immune disorders. Making a diagnosis can be challenging and first assisted by electrophysiologic and sometimes pathologic sampling, with autoimmune biomarkers providing increased assistance. The importance of autoimmune neuropathies cannot be overstated as many of the disorders are treatable and reversible. In this chapter, we provide an overview of how the field developed and describe some of the ongoing challenges.

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