Presenter Information

Claire Andries, LSUHSC

Location

LSU Health Science Center - New Orleans

Event Website

https://alliedhealth.lsuhsc.edu/admin/sahpresearchday.aspx

Document Type

Event

Start Date

8-4-2024 3:00 PM

End Date

8-4-2024 5:00 PM

Description

Fluoroquinolones, a class of broad-spectrum antibiotics, have several adverse side effects, including Achilles tendinopathy and rupture. The mechanism is thought to be from inhibition of collagen synthesis leading to decreased tendon integrity. While there is no standardized treatment for fluoroquinolone-associated Achilles tendinopathy, it is recommended to discontinue medication and approach rehabilitation with increased caution. Current literature supports rehabilitation for Achilles tendinopathy to include four phases of exercises: isometric, isotonic and heavy slow resistance, increase in speed and energy storage, and sport specific. The purpose of this case report is to examine the relationship between fluoroquinolone use and Achilles tendinopathy and the effect on physical therapy treatment.

The patient selected for this case report is a 29-year-old female with 3-year history of bilateral Achilles tendinopathy that began after taking Levofloxacin, a type of fluoroquinolone antibiotic. Following 5 treatment sessions, the patient’s subjective improvements include decreased pain, ability to perform ADLs, and functional mobility as evidenced by the LEFS. Objectively, the patient made improvements with bilateral ankle ROM, strength, swelling via figure 8 measurement, joint mobility, and balance. Following conservative methods recommended in current research, the therapy interventions selected were effective in managing fluoroquinolone-associated Achilles tendinopathy. Isometric exercises were utilized for pain relief, isotonic exercises for muscle strength, tendon stiffness, and neuroplasticity, and heavy slow resistance training for strengthening the tendon matrix itself. Despite challenges in developing a specific care plan, future studies should focus on standardizing treatment protocols and exploring chronic tendon changes associated with fluoroquinolone use.

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Apr 8th, 3:00 PM Apr 8th, 5:00 PM

The Effect of Fluoroquinolone use on the Development and Physical Therapy Rehabilitation of Achilles Tendinopathy: A Case Report

LSU Health Science Center - New Orleans

Fluoroquinolones, a class of broad-spectrum antibiotics, have several adverse side effects, including Achilles tendinopathy and rupture. The mechanism is thought to be from inhibition of collagen synthesis leading to decreased tendon integrity. While there is no standardized treatment for fluoroquinolone-associated Achilles tendinopathy, it is recommended to discontinue medication and approach rehabilitation with increased caution. Current literature supports rehabilitation for Achilles tendinopathy to include four phases of exercises: isometric, isotonic and heavy slow resistance, increase in speed and energy storage, and sport specific. The purpose of this case report is to examine the relationship between fluoroquinolone use and Achilles tendinopathy and the effect on physical therapy treatment.

The patient selected for this case report is a 29-year-old female with 3-year history of bilateral Achilles tendinopathy that began after taking Levofloxacin, a type of fluoroquinolone antibiotic. Following 5 treatment sessions, the patient’s subjective improvements include decreased pain, ability to perform ADLs, and functional mobility as evidenced by the LEFS. Objectively, the patient made improvements with bilateral ankle ROM, strength, swelling via figure 8 measurement, joint mobility, and balance. Following conservative methods recommended in current research, the therapy interventions selected were effective in managing fluoroquinolone-associated Achilles tendinopathy. Isometric exercises were utilized for pain relief, isotonic exercises for muscle strength, tendon stiffness, and neuroplasticity, and heavy slow resistance training for strengthening the tendon matrix itself. Despite challenges in developing a specific care plan, future studies should focus on standardizing treatment protocols and exploring chronic tendon changes associated with fluoroquinolone use.

https://digitalscholar.lsuhsc.edu/ahrd/2024/2024/3