Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH)

Authors

Tung Sung Tseng, LSU Health Sciences Center - New OrleansFollow
Wei Ting Lin, Tulane University School of Public Health and Tropical Medicine
Peng Sheng Ting, Tulane University School of Medicine
Chiung Kuei Huang, Tulane University School of Medicine
Po Hung Chen, Johns Hopkins School of Medicine
Gabrielle V. Gonzalez, LSU Health Sciences Center - New OrleansFollow
Hui Yi Lin, LSU Health Sciences Center - New OrleansFollow

Document Type

Article

Publication Date

9-15-2023

Publication Title

Nutrients

Abstract

Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. However, the impact of different types of SSBs, including artificially sweetened beverages (ASBs), is not clear after controlling for total sugar intake and total caloric intake. The aim of this study was to examine the association between the consumption of different SSBs and the risk of NAFLD and NASH in US adults. The representativeness of 3739 US adults aged ≥20 years old who had completed 24 h dietary recall interviews and measurements, including dietary, SSBs, smoking, physical activity, and liver stiffness measurements, were selected from the National Health and Nutrition Examination Survey 2017–2020 surveys. Chi-square tests, t-tests, and weighted logistic regression models were utilized for analyses. The prevalence of NASH was 20.5%, and that of NAFLD (defined without NASH) was 32.7% of US. adults. We observed a higher prevalence of NASH/NAFLD in men, Mexican-Americans, individuals with sugar intake from SSBs, light–moderate alcohol use, lower physical activity levels, higher energy intake, obesity, and medical comorbidities. Heavy sugar consumption through SSBs was significantly associated with NAFLD (aOR = 1.60, 95% CI = 1.05–2.45). In addition, the intake of ASBs only (compared to the non-SSB category) was significantly associated with NAFLD (aOR = 1.78, 95% CI = 1.04–3.05), after adjusting for demographic, risk behaviors, and body mass index. A higher sugar intake from SSBs and exclusive ASB intake are both associated with the risk of NAFLD.

PubMed ID

37764782

Volume

15

Issue

18

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Tseng, Tung Sung; Lin, Wei Ting; Ting, Peng Sheng; Huang, Chiung Kuei; Chen, Po Hung; Gonzalez, Gabrielle V.; and Lin, Hui Yi, "Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH)" (2023). School of Public Health Faculty Publications. 283.
https://digitalscholar.lsuhsc.edu/soph_facpubs/283