Document Type
Article
Publication Date
2-27-2025
Publication Title
Physiology & Behavior
Abstract
Chronic pain affects over 20% of the global population and contributes to the vast burden of psychiatric illness. While effective treatments for chronic pain remain limited, both alcohol and cannabis have been used for centuries to manage pain and closely associated negative affective symptoms. However, persistent misuse of alcohol and/or cannabis in such a negative reinforcement fashion is hypothesized to increase the risk of severity of substance use disorders (SUDs). The current review describes neurobiological evidence for the analgesic efficacy of alcohol and primary cannabis constituents and how use or co-use of these substances may influence SUD risk.
PubMed ID
40023207
Volume
294
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Lee, Sumin and Edwards, Scott, "Alcohol and cannabis use for pain management: Translational findings of relative risks, benefits, and interactions" (2025). School of Medicine Faculty Publications. 3654.
https://digitalscholar.lsuhsc.edu/som_facpubs/3654
10.1016/j.physbeh.2025.114867
Included in
Behavior and Behavior Mechanisms Commons, Chemical Actions and Uses Commons, Pathological Conditions, Signs and Symptoms Commons