Document Type
Article
Publication Date
7-11-2020
Publication Title
Endocrinology (United States)
Abstract
The current COVID-19 pandemic is the most disruptive event in the past 50 years, with a global impact on health care and world economies. It is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a coronavirus that uses angiotensin-converting enzyme 2 (ACE2) as an entry point to the cells. ACE2 is a transmembrane carboxypeptidase and member of the renin-angiotensin system. This mini-review summarizes the main findings regarding ACE2 expression and function in endocrine tissues. We discuss rapidly evolving knowledge on the potential role of ACE2 and SARS coronaviruses in endocrinology and the development of diabetes mellitus, hypogonadism, and pituitary and thyroid diseases.
PubMed ID
32652001
Volume
161
Issue
9
Recommended Citation
Lazartigues, Eric; Qadir, Mirza Muhammad Fahd; and Mauvais-Jarvis, Franck, "Endocrine Significance of SARS-CoV-2's Reliance on ACE2" (2020). School of Medicine Faculty Publications. 1838.
https://digitalscholar.lsuhsc.edu/som_facpubs/1838
Included in
Cardiology Commons, Endocrinology, Diabetes, and Metabolism Commons, Medical Pharmacology Commons, Virus Diseases Commons